This hypothesis, originally based on studies of human antibody response to various strains of influenza viruses, was further supported by sequential experimental infections in ferrets [26], [27] and has been an important concept in the understanding of influenza immunology and a challenge for influenza vaccine development [28], [29].
Janeway [ 4] and Poltorak et al. [ 7] proposed a central concept in the understanding of the innate immune system: the identification of infectious agents by means of conserved structural features through pattern recognition receptors (PRRs).
This study used questionnaire data from three successive cohorts of nurse prescribing students (n = 84) to evaluate the use of RLOs focussed around pharmacology concepts to promote the understanding of these concepts in students.
She looks at key concepts in the current understanding of Borderline Personality Disorder, which is characterized by feelings of emptiness or loss of self, impulsive or self-destructive behaviour, bursts of anger and unstable relationships.
The experiment is a valuable step in establishing the viability of the reference concept, and making progress in the understanding of the behavior of buffer material under thermal-hydro-mechanical (THM) coupled condition.
The first concept, immune-mediated regulation of bone loss, has been studied intensively in recent years and has become a well-developed concept that is instrumental in the understanding of the different forms of bone loss in the course of rheumatic diseases.
Epistemological perspective: The epistemological perspective of educational implementation reflects the "concepts, theories and central problems in the understanding of knowledge and justification" (Audi, 2011, page. xiii) that underlie the proposed designs and implementations.
The observations have led to the formation of an exciting concept: adipose tissue hypoxia (ATH), in the understanding of major disorders associated with obesity [16].
