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As a proof of concept, we compared different variants of kidney-derived fibrillated matrices in cell culture experiments referring to specific requirements of kidney tissue engineering approaches.
To validate this concept we compared the strength of concordance between LSM and FT, for the diagnosis of advanced fibrosis stage, between a population including only subjects who fulfilled the quality criteria as recommended by the manufacturer (low risk profile of false negatives/positives) and a population not fulfilling these quality criteria (high risk of false negatives/positives).
For proof of concept, we compared the consensus and H37Rv genomes as reference standards for phylogenetic analysis, SNP detection and secondary analysis of WGS data.
To further highlight this concept, we compared signature enrichment in the 'Sepsis' and 'No Sepsis' groups following further separation based on microbial culture results.
In order to determine the diagnostic value of the sentinel lymph-node concept, we compared the pathohistological results of sentinel nodes with the respective neck dissection specimens.
As proof of concept, we compared the DNA methylation profiles of bovine sperm and blastocysts and performed validation by pyrosequencing on selected DMRs.
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As a proof of concept, we compare the performance of our estimated measurements and true measurements at each candidate time point, assessing the ability of estimated measurements to predict which candidate time point most reduces a given uncertainty metric.
When we match two concepts, we compare their contents in these three dimensions, and acquire the corresponding similarity in each dimension.
In our proof-of-concept experiment, we compared the performance of BSI and ELISA with analysis of human serum and plasma spiked with the protein biomarkers of interest.
For proof-of-concept purposes we compared the unfolding and refolding dynamics of a previously studied stable 20 base-pair (bp) long DNA hairpin 13 using conventional dsDNA linkers versus using stiff ten-helix bundle linkers.
For concept verification, we compare several scholars' models as well as leading feature selection methods with the proposed method.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com