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The method is based on a proof of concept reported by Pimestein et al. (2011) for the use of an internal soil standard (ISS), a concept adopted from the wet chemistry discipline.
The remainder of the dynamic VNS corresponds to the reduced VNS concept reported by Hansen and Mladenović (2005), so we do not use an additional local search step after the shaking step.
To control bisulphite conversion efficiency, all samples were subjected to quantitative methylation-specific PCRs (qMSP) using the concept reported by Campan et al (2009) and van der Horst et al (2004).
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Interestingly, some of the concepts reported by multiple students were not a main focus of the lesson, but are valuable lessons for how evolution proceeds (e.g., evolution takes place over a long time rather than in one generation).
Missing concepts reported by individual patients with ACO included sinus problems, hoarse or raspy voice, feeling disoriented, throat clearing or irritation, animal hair as an asthma trigger, the need to use rescue medication before the day has begun, changes in asthma medication use, and response time for recovery following asthma medication.
Only few concepts reported by the patients could not be coded with ICF categories.
Items were not generated for other concepts reported by participants (headache, snoring, burning chest), as they were mentioned in only one of the four focus groups and by fewer than two participants for each concept.
For example, clinicians suggested that some of the concepts reported by adolescents and their caregiver as an impact of ADHD, such as emotional lability, were likely to be part of the psychopathology of the disease rather than an impact of the core symptoms of ADHD.
In-situ SBM was designed based on on-slide SBM [14] which was adapted from a concept as reported by Nuovo et al [25].
A similar concept was reported by Qin and co-workers.
In December 2009, a new generation EGFR inhibitor concept was reported by a group in Dana-Farber Cancer Institute [ 6].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com