The concept has been previously applied for searching binding motifs of RNA-binding proteins (Hiller et al., 2006).
Criticality and degeneracy are both important concepts for understanding how complex systems normally operate and how they fail in disease states, but neither concept has been previously applied to help decipher the pathogenesis of neuropathic pain.
We have previously applied the concept of studying a reference population and defined a group of low-risk primiparous women (Caucasian, 20 40 years of age, with singleton spontaneous pregnancies and spontaneous onset of delivery) in a Danish cohort [ 11].
The conceptualization process has led to a much richer and more extensive set of concepts relevant to assessing the needs of people with back pain than is captured in the outcome tools previously applied.
Using innovation management models previously applied to other industries, Clayton M. Christensen, a Harvard Business School professor, argues in "The Innovator's Prescription" that the concepts behind "disruptive innovation" can reinvent health care.
I have previously applied to the Graduate School of Arts and Sciences.
I had previously applied and was thrown by the exercises.
