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In this chapter, we provide some proof of concept examples of such efforts for engineering disease models.
Nowadays architects commonly use the 'coupled space concept'; examples are mezzanines, half-open office spaces and exhibition rooms.
To facilitate understanding of the concept examples of nudges were provided including the distancing of color printers to prevent unnecessary use of color prints; the use of colored bin bags to ease the separation of waste; and the provision of smaller plates in a cafeteria to prevent eating large portions.
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To illustrate the proposed approach, a proof of concept example is presented.
The model derivations and reformulations to cluster-based models are presented and the usage highlighted through a simple proof of concept example and a case study.
This approach is demonstrated on illustrative cases and a naval ship concept example to illustrate the importance of identifying cascading failures in early stage design.
As a proof of concept example, the method was first applied to the Sears et al. carnivoran dataset [ 13].
The recent description of a relapse patient with BRAF mutation responding spectacularly to BRAF inhibitor is one such proof of concept example [ 42].
For this simulation exercise it was explicitly not our aim to derive definitive dose regimens for this infection, but only to provide a motivating proof of concept example.
Proof-of-concept examples are used to demonstrate the tools.
Using several proof-of-concept examples, we demonstrate that I-optimal designs offer both flexibility and small variances of prediction.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com