Exact(2)
Where possible, initial metabolite concentrations were updated according to in-house values; otherwise recent literature data for respiro-fermentative, non-starved cells were used [24].
When the morphostat concentrations were updated, these negative values mathematically prevented the morphostat concentration in the stroma from directly influencing the morphostat concentration of the epithelial cells on the other side of the block, which is the mathematical equivalent of preventing diffusion across the block.
Similar(58)
After all receptors have been updated at each time step, calcium and PTH concentrations are updated using the difference equations in (1 - 3).
Then the cell density and external metabolite concentrations are updated by solving standard differential equations as detailed in [ 34].
The biomass and substrate concentrations are updated at each time interval as shown in Equations 4 and 5, respectively.
Numerical integration of the pathway was conducted in a two step process, with all the fluxes f → (t ) being calculated from metabolite concentrations and then all the metabolite concentrations being updated from the net fluxes.
The reaction velocity v is converted from M.reactions per second to reactions per millisecond (that is, per timestep) in the total volume and the appropriate polysaccharide concentrations are updated accordingly.
Once the velocity value and interfacial configurations are obtained, surfactant concentration is updated using the transport equation.
Based on these equations, the 24-hour concentration was updated daily in the simulation model.
Data were updated April 14 , 2005
Searches were updated through March 30 , 2008
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