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Time-dependent antibiotics, such as β-lactams or glycopeptides, require drug concentrations to be maintained above the MIC throughout the dosing interval.
The elevated EGP is likely a compensatory response that enables normal plasma glucose concentrations to be maintained in the presence of sustained UGE, but the mechanism(s) leading to the increased EGP is not known.
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The deep-water, deep-basin model accounts for replenishment of the basin across the barrier or sill, with slow, continual buildup of thick evaporites made possible by the seaward escape of brine that allows a constant brine concentration to be maintained.
The hemoglobin concentration to be maintained in pregnancy has not been established.
Immobilization prevents enzyme washouts and allows a high enzyme concentration to be maintained in a continuous reactor.
Furthermore, the complexed calcium (total minus free calcium) virtually disappeared from the hemolymph on day 10 in 10 and 50 ppt, indicating that all the hemolymph calcium was ionized, and the concentrations appeared to be maintained at acclimated values.
In cows, non-pregnant circulating INSL3 concentrations appear to be maintained during the first trimester of pregnancy, with possibly a small decline at day 48.
Consequently, spatial and temporal regulation of cellular cAMP concentrations needs to be maintained under tight control.
To be efficient, sufficient chaperone concentrations need to be maintained in the ER lumen (Butters et al, 2005).
If anaesthesia was achieved and maintained during the 0-15 minute section, the target concentration was to be maintained for the 15-30 min section; otherwise, after the first 0-15 minute section, the target concentration was to be increased by 50% for the remaining 15-30 min section.
Building upon recent successes in mathematical modeling of the human glucose insulin system, we show that both food intake and insulin therapy likely demand increasingly precise control over insulin sensitivity if oscillations at a healthy average glucose concentration are to be maintained.
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CEO of Professional Science Editing for Scientists @ prosciediting.com