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Interestingly, the inhibitory T4C concentrations tested on epimastigotes (between 0.1 and 1.0 mM) were not toxic to mammalian cells (IC50 = 11.4±0.36 mM) (Figure 6).
The decoction inhibited the growth of two of the six bacterial strains tested viz., S. flexneri (EC50 value 0.98% ± 0.2%) and V. cholerae (EC50 value 2.88% ± 0.36%) whereas there was no effect of quercetin at any of the concentrations tested on the growth of all six strains tested (data not shown).
The results of this study demonstrate an absence of any mutagenic activity in leaf extracts of B. verbascifolia, B. correifolia, B. fagifolia and B. intermedia, at all the concentrations tested on the four S. typhimurium strains, since the number of revertant colonies observed on each test plate was less than twice that in the negative control [ 7].
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According to our previous cell viability analyses, the first higher concentration tested on HaCaT cells was not cytotoxic.
The compounds lowered secreted Aβ in conditioned media at the concentrations tested for effects on APP metabolites.
After exposure for 96 h to different concentrations of culture filtrates from three Alternaria alternata isolates, the calli exposed to 100 and 50% concentrations of the filtrates were significantly more damaged than other concentrations tested, based on a visual rating scale.
They were dissolved in Millipore-filtered seawater and used in concentrations tested previously on cyprids of parasitic barnacles (Rhizocephala) [ 17]: 3-isobutyl-1-methylxanthine (IBMX at 4.5 μM), 20-hydroxyecdysone (20-HE at 208 μM, 20.8 μM, 2.08 μM, 1.04 μM and 208 nM), and juvenile hormone (JH at 37.5 nM, 375 nM and 3.75 μM).
Therefore, IL-6 seems to confer, at least at the concentrations tested, less neuroprotection on axotomized RGCs than CNTF in vivo, but nevertheless potently induces axonal regeneration.
No significantly negative effects of terbuthylazine-2-hydroxy at the concentrations tested (0.0029 3.5 mg/L) on hatching and embryo viability were observed.
CaCl2 and A23187 themselves at the concentrations tested had no effects on C. albicans growth.
As predicted, compound 26 at all concentrations tested had no effect on EGF-induced MAPK activity in HeLa cells in the presence or absence of RKIP (Figure 6).
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