Sentence examples for concentrations required for a from inspiring English sources
We will discuss the relevance of pharmacological data as a function of doses or concentrations required for a given effect and of concentrations achieved in the target tissues.
When compared to normothermia, hypothermia (27 °C) increased the Na2S concentrations necessary to induce inhibition of mitochondrial respiratory activity (from < 1 μΜ to 2-4 μΜ), and nearly doubled the Na2S concentrations required for a 50 % reduction in mitochondrial respiratory activity [ 16], [ 45].
All these factors mean that it is difficult to extrapolate relevant in vivo concentrations of toxicants from in vitro results alone, and typically, the concentrations required for a given effect in vitro will be substantially higher than those required for parallel effects in vivo (Coecke et al. 2007).
Concentration required for a 50% inhibition of viability (IC50) was determined graphically.
As Weibrich [ 15] reported, the PLT concentration required for a positive PRP effect on bone regeneration spanned a limited range.
The spin coating experiments, carried out on flat substrates, were used to estimate the concentration required for a conformal coating.
The drug concentration required for a 50% reduction in the net protein increase (GI50) was calculated as described previously.
The growth inhibition of the yeast cells was calculated and expressed as MIC (minimum inhibitory concentration) and IC50 (concentration required for a growth reduction of the 50%).
With nitroimidazoles, definition of the relationship between one-electron reduction potential and the concentration required for a given degree of enhancement identified optimal physicochemical characteristics for radiation sensitisation (Adams et al, 1977).
The minimal PLCζ concentration required for a physiologic pattern of Ca2+ oscillations was 0.0167 mg/mL, indicating that the amount of human PLCζ in mouse eggs able to induce Ca2+ oscillations and early embryogenesis was ∼80 fg/egg.
The very low concentration required for a toxic response led to the hypothesis that ADDL-induced toxicity may be specific and it was postulated that such toxicity mightinvolve specific cell-surface receptors [ 9, 68].
