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To experimentally validate the capability of our model to predict the relative p21 concentrations regulated by cooperative miRNAs, we selected miR-572 and miR-93 as a case study.
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Oxygen after extubation was supplied either by nasal prongs or facial mask with oxygen concentration regulated by Venturi effect.
The intracellular calcium concentration, regulated by calcium ions, is important for biochemical reactions.
If iron were liberated from ferritin directly in the cytosol, and its concentration regulated by a feedback mechanism (de Domenico et al. 2006), one would expect a preserved cytosolic concentration of chelatable iron for quite a while.
Since systemic glucocorticoid levels are generally normal in patients with common forms of obesity or overweight type 2 diabetics,[ 21] it is speculated that the intracellular glucocorticoid concentration, regulated by 11β-HSDs, is responsible for the metabolic abnormalities.
In turn, cytoplasmic Ca2+ concentrations are regulated by mitochondria.
The ionic concentrations are regulated by servo-mechanisms which comply a conductimetric sensor with dosimetric pumps; these pumps introduce appropriate quantities of constituents.
Extracellular 5-HT concentrations are regulated by 5-HT transporters (SERTs), indicating that these transporters may be important molecular targets underlying individual differences in impulsivity and drug abuse vulnerability.
Their intracellular concentrations are regulated by two enzyme systems: cyclases, which catalyze formation of cAMP and cGMP from ATP and GTP, respectively, and cyclic nucleotide phosphodiesterases (PDEs), which cleave the high-energy 3′5′ cyclic phosphate bond of cAMP and cGMP to yield 5′AMP and 5′GMP, respectively.
Final sodium concentrations are regulated by dialysis machines via augmentation with sodium hydrocarbonate.
ABA concentrations are regulated by NCEDs in avocado fruit, a climacteric fruit [ 72].
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