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The information for controlling cell fate is transmitted by concentrations of cellular signaling molecules.
MRSI provides information about the relative concentrations of cellular metabolites in the prostate such as citrate and choline [5, 44, 55].
By contrast the slower intercellular variability in the onset times for AI response and in the overall luminescence output is more suggestive of extrinsic noise originating in the variable concentrations of cellular components such as ribosomes, polymerases, or in different stages in the growth cycle, etc. [34].
Further, secretory granules contain the highest concentrations of cellular IP3R/Ca2+ channels in neuroendocrine cells [39], and the IP3R/Ca2+ channels of secretory granules are ∼7-fold more sensitive to IP3 than those of the ER [40], which means that secretory granules will release Ca2+ in response even to one-seventh the IP3 concentration that is required to induce Ca2+ release from the ER.
It is likely that this mechanism is operating also in vivo since the expression of p47phox, that reasonably reflects the activity of NADPH-oxidase, was much higher in the PBMC of heavy smokers who had the highest concentrations of cellular PGPC, POVPC and PEIPC, than in moderate smokers or non-smokers.
The concentrations of cellular proteins vary over seven orders of magnitude [ 54, 81, 84].
Similar(39)
Some of the places with the lowest concentrations of cellular-only households were also the oldest.
In fact, the wealthiest areas -- New England, New York, California -- had some of the lowest concentrations of cellular-only households.
It had one of the lower concentrations of cellular-phone only households, even though its median age makes it the sixth youngest state, according to 2009 census data.
When a rise in the concentration of cellular calcium results from the opening of calcium-selective channels, the membrane's calcium pumps restore the low concentration.
In this study, the concentration of cellular protein carbonyls in brain was significantly increased by 38% within 1 h after cold exposure (from 28°C to 18°C) of zebrafish (Danio rerio).
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