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The experiments shown in Figure 4 were all performed at a concentration of hArc of 1 mg/ml (22 μM subunit) and, as expected from the Law of Mass Action, higher concentrations exacerbated the oligomerization/aggregation of the protein (results not shown).
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Superoxide production at low oxygen concentration exacerbates oxidative stress in men with varicocele.
A growing body of literature suggest either the PGE sources (self-reported by the subjects), or their directly quantified concentrations exacerbate airway problems.
However, the slope deviation from linearity occurs at the higher pressures, particularly in the case of GAH NAG with 1 14 because of the concentration polarization exacerbated owing to NAG accumulation at the membrane surface by the driving pressure.
The application of nitrogen fertilizer and elevation of atmospheric CO2 concentration exacerbate aphid infestation [ 3].
But with demand outstripping supply in almost every community, well-intentioned practices of rationing this scarce resource to those most in need have altered our use of social housing from a public good for all, to one that has exacerbated concentrations of deprivation.
However, high concentrations of propranolol exacerbated transmural gradients of repolarization in Scn5a+/Δ hearts, which resulted in a proarrhythmic effect unmasked in provoked arrhythmogenesis studies in which premature stimuli, acting as surrogate EADs, imposed upon an arrhythmic substrate.
This stress-concentration would exacerbate tissue damage in the area surrounding the collapse [33].
IL-6 is a vital procoagulant cytokine, and it contributes to enhance plasma CRP concentration, which exacerbates inflammatory and procoagulant responses [67].
Because the majority (>80 90%) of glucose disposal during the euglycemic insulin clamp occurs in muscle, these results demonstrate that a physiologic elevation in the plasma insulin concentration will exacerbate the underlying muscle insulin resistance.
This strong drive towards further concentration has been exacerbated by the decision to pour massive public resources into the building of the £700 million Crick Institute in central London.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com