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The Concentration Response Function (CRF) in equation 1 determines the relationship between an increase in Pbair and the corresponding increase in Pb impacts.
26 Considerable variability existed between individuals in both the salivary threshold and the slope of the blood: saliva concentration response function.
The proportional reduction is the same for admissions and emergency visits because in this example the concentration response function is simply scaled based on the relative frequency of the two types of outcome.
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The next section discusses evidence for the shape of the concentration-response function.
Note: References for health endpoints refer to the concentration-response function applied.
In addition, we note that the magnitude of the public health damages is sensitive to the concentration-response function applied.
However, open questions about the shape of the concentration-response function at low and high concentrations still exist.
Predicted premature mortality increases to a little over 5,000, and based on the concentration-response function used, ranges from 2,400 to over 6,300.
Marginal concentration changes are related to a concentration-response function for mortality, with a value of statistical life approach used to monetize the impacts.
The uncertainty illustrated in Table 2 does not incorporate the uncertainty about the shape of the concentration-response function at high concentrations.
Ohio and Pennsylvania follow, with approximately 260 predicted premature mortalities each (based on the midpoint of the combined expert elicitation concentration-response function).
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