At baseline among the males, the difference in the mean hemoglobin concentration of the intervention group (10.9 mg/dL) and control (10.6 mg/dL) was not significant (t=0.61, P=0.55).
This high reduction is probably caused by the concentration of technical interventions at intersections.
In contrast with the results obtained when the effects were expressed relatively, a significant (P < 0.01) interaction between PS intake and baseline TG concentrations was observed on absolute end-of-intervention concentrations.
At the end of 6 months, the differences in mean body mass index (BMI) and hemoglobin concentrations of the intervention and control groups were compared using the Student's t-test.
Freezing and thawing protocols were identical for embryos in the control (conventional concentration of sucrose) and intervention (increased concentration of sucrose) groups, but the freezing and thawing solutions differed.
Next, we tested for association between each SNP and change in lipid concentration following 24 weeks of intervention (change calculated as final value minus baseline), adjusted for baseline values of respective trait, age, gender and BMI.
Other potential sources of heterogeneity considered were concentration of LA, timing of interventions as related to surgery, and the use of image guidance.
Although we considered concentration of LA, timing of interventions as related to surgery, and the use of image guidance as potential sources of heterogeneity, we did not have sufficient number of studies to carry out further subgroup analysis.
For the absolute changes, analysis was done on end-of-intervention serum lipid concentrations while adjusting for baseline concentrations.
It was not possible to subgroup by equol-producer status (as not enough studies reported data on equol concentrations) or by intensity of intervention (as all studies provided a supplement or food and none provided advice alone).
