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Passage with a higher drug concentration of compound 2 selected higher level resistant viruses with a double mutant L26I + A30T.
Fold change relative to vehicle (F) was calculated as the ratio between the biomarker concentration of compound treated (R1) and non-treated (R2) microtissues where F = (R1/R2) − 1.
Interestingly, the shift in the IC50 required to suppress the re-engineered resistant mutant viruses closely matched the concentration of compound used during the selection of drug resistance.
Concentration of compound in soil.
The MIC was defined as the lowest concentration of compound giving complete inhibition of visible growth.
The higher shift in ΔT m for higher concentration of compound signifies binding.
6 mg/disc concentration of compound was impregnated on the discs.
A SDS-PAGE of the reaction products treated with different concentration of compound.
MIC values were defined as the minimum concentration of compound that inhibited visible microbial growth.
B The relative activity of polymerase under increasing concentration of compound.
The second principal component (PC2) was the concentration of compound C8G (scores 0.894) (Additional file 2: Table S4).
More suggestions(15)
concentration of soil
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