Sentence examples for concentration of action from inspiring English sources
Thus, alternative strategies that would enhance cellular sensitivity to As2O3, thereby lowering its concentration of action, would be helpful.
Sometimes the concentration of the action makes the story impossible to follow – the opening section is particularly impenetrable.
Our findings suggest that these polymers operate with a concentration-dependent mechanism of action: at low concentrations permeation and DNA binding occur without membrane disruption, while at high concentrations complete disruption of the membrane occurs.
The aim of this work was to evaluate the in vitro effect of chitosan (concentration and time of action) treatment on enamel de-remineralization behavior upon a pH cycling assay.
Concerns about the concentration and duration of action of bupivacaine have also been reported [ 41].
In vitro investigations demonstrated that both E2 and E3 can stimulate BC cells, but the effect largely depends on their concentration and duration of action [ 48].
DPP-4 inhibitors are a new class of anti-diabetic drugs that improve glucose metabolism by raising the active concentration and duration of action of glucagon-like peptide (GLP -1 [ 2- 5].
Topics covered in this review include the rationale for developing a hypoxic cytotoxic agent, the cytotoxicity of SR 4233 as a function of oxygen concentration, the mechanism of action of the drug and its intracellular target and the in vivo evidence that the drug may be useful as an adjunct both to radiotherapy and chemotherapy.
In this case, interindividual variability in transporter activity can result in a lack of correlation between plasma concentration and concentration at the site of action between individuals.
However, concerns associated with its narrow therapeutic index and its concentration-dependent mechanism of action are rising.
This paper critically reviews the evidence for read-across, and finds that few studies include plasma concentrations and mode of action based effects.
