Sentence examples for concentration elimination from inspiring English sources
Times to reach maximum drug concentration in plasma, maximum drug concentration, elimination rate constant, and renal clearance were not influenced by different generic products with a nonsignificant P value greater than 0.05.
From kinetic viewpoint, the area under the plasma concentration versus time curve to last time, area under the plasma concentration curve to infinity, peak plasma concentration, time of peak plasma concentration, elimination rate constant and terminal half-life were observed.
Plasma concentration vs time profile was assessed for the set of PK variables defined in the phase I study (Van Kesteren et al, 2000): area under the curve, maximum plasma concentration, elimination half-life, total plasma clearance and volume of distribution at steady state.
Maximal plasma concentration (Cmax), elimination rate constant (ke) and elimination half-life (T1/2e) were derived from the model.
Another possibility for the observed decay in their concentration are elimination reactions.
Neither urinary KIM-1 concentration or elimination correlated with any renal and hepatic function parameter.
AUC, area under the curve; CL, total clearance; Cmax, peak concentration; t1/2, elimination half-time; Vd, volume of distribution.
Indeed, it may change due to a variety of factors, e.g., with concentration if elimination is mixed order.
Maximum concentration (Cmax), elimination half-life (t1/2), area AUC, Cmin, volume of distribution (Vd), clearance (CL), fraction unbound, and sieving coefficient (Sc) were evaluated.
Except for the difference in dose at which bosentan pharmacokinetics deviate from being proportional, the pharmacokinetic characteristics of bosentan in children and adults, in terms of time to maximum concentration and elimination, are comparable [ 11, 13].
Because the metabolite 14-hydroxy derivative is primarily excreted in the urine, an increase in area under the plasma concentration-time curve, peak plasma concentrations and elimination half-life are expected in patients with kidney disease (but not those with hepatic impairment).
