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Restaurants require concentration and timing.
The disease or functional outcome will depend on the stressor, its concentration and timing.
Intriguingly, however, the incubation of ES cells with H2O2 either enhances or impairs the cardiomyogenic program, dependent upon the concentration and timing during differentiation suggesting both a dose-dependency and a cellular competency in the response to ROS [63,92,96].
This game requires a lot of concentration and timing to play correctly and you don't want to keep trying if you are getting frustrated.
By testing out the optimal concentration and timing of adding FGF4 and RA, we show for the first time that RA and FGF4 in a dose-dependent manner synergistically induce differentiation into PDX1+ cells (on average 32%).
"The key is focus, concentration and timing," Froemming said.
Similar(41)
Santiago Ropero (Hospital 12 de Octubre, Madrid, Spain) showed, however, that combination treatment of breast cancer cells with herceptin and tamoxifen could be additive, synergistic, or antagonistic for cell growth, depending on concentrations and timing.
The effects of PLGA and PLLA degradation medium, as well as different lactate concentrations and timing of exposure on chondrocytes proliferation and cartilage-specific matrix synthesis were investigated by various techniques including global gene expression profiling and gene knockdown experiments.
The hormone concentrations and timing of application for this study were motivated by the existing literature; however, the use of a scaffold-free system may justify additional optimization of hormone dosing, timing, and duration.
We observed a marked heterogeneity in pH threshold, concentration, amount, and timing for bicarbonate administration in various studies.
We have found marked heterogeneity and no clear evidence, with regards to the threshold for, concentration, amount, and timing of bicarbonate administration.
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