Sentence examples for concentrating ability from inspiring English sources

With advancing age the concentrating ability of the kidney falls, so that a greater volume of water is required to excrete the same amount of waste material.

The reduced concentrating ability of the kidney results from a loss of some of the nephrons, the functional elements of the kidney, and the reduced activity of cellular enzymes.

This loss in concentrating ability is probably partially offset by a decrease in the excretory load because of reduced activity, alterations in food intake, and the reduction in muscle mass of the elderly.

Impairments in urinary concentrating ability had however progressed in the lithium-treated group.

Most bipolar patients experience a reduction in urinary concentrating ability within a few weeks of starting lithium treatment.

This phenomenon is explained by the combination of large volumes of (approximately) isotonic fluids and a reduced urinary concentrating ability.

This results in a reduction of the kidneys' capacities to preserve free water, leading to impaired concentrating ability and the production of excessively dilute urine (Gitlin 1999).

The most frequent renal lithium effect is a decrease in urinary concentrating ability, which clinically manifests itself by polyuria and polydipsia of various intensities.

Additional factors that predispose to hypernatremia include a reduced urinary concentrating ability, the inability to express thirst, no free access to water, and increased insensible losses [5, 6].

In this group of patients, we demonstrated a significant relationship of the GSK-3β genotype only with one aspect of kidney function, the urinary concentrating ability.

It has been hypothesized that such a mechanism may underlie the lithium-induced impairment of urinary concentrating ability (Grünfeld and Rossier 2009).