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Studies with transgenic parasites or heterologous expression systems have attributed PfCRT-mediated CQ resistance to drug efflux out of the low-pH digestive vacuole, where CQ becomes diprotonated, concentrates up to 1,000-fold 1,000-foldy binding to heme products and preventing heme detoxificactsn [ 17– 20].
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The cell lysate, which could only be concentrated up to a concentration of 80 mg mL−1, shows no significant compression effect at its highest concentration.
Our structural studies were initiated with proteins that contained N-terminal His tags, and surprisingly, we found that the His-tagged P23T mutant protein could be concentrated up to 90 mg/mL (no further concentration was attempted).
The deep-concentrating experiments revealed that a feed of 10 g/L could be successfully concentrated up to about 400 g/L with a rejection efficiency still greater than 99.9%.
Each sample was concentrated up to ~50 μl.
In the first MD step seawater is concentrated up to the saturation point of CaCO3.
Furthermore CO2 in the exhausted gas is required to be concentrated up to more than ca. 30%.
PCR products of the expected size were obtained from samples concentrated up to 102 cfu ml− 1.
With low pH of the raw water (pH 2.2) in the first stage, chromate was presented as HCrO4− and monovalent ions (HCrO4−, NH2SO3−, Na+ and Cl−) were able to pass through the membrane thus chromate was concentrated up to 191%.
With recent advances, it has become very difficult to concentrate up on a particular species as a model plant.
Similarly, the skin deformation for the fine grating scale, for which the surface period was 2 mm, was predicted to concentrate up to 40 50 Hz.
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