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While in the past comparative genomics has concentrated on sequencing single genomes and parts of genomes, current excitement lies with the sequencing of environmental communities.
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We have overlooked the molecular mechanisms that govern compositional (sequence) variations, but concentrated on sequence variation itself.
Whereas some studies have focused on analysing only the chemistry [ 34,35], other studies concentrated on sequence and structure evolution [ 15,22 ].
Many of the comparisons carried out between humans and chimpanzees have concentrated on sequences deleted in the human genome in comparison with the ancestral state.
Meanwhile, studies of longer repetitive elements have concentrated on sequences of a few hundred to a few thousand base pairs, e.g., transposable elements, that (with the exception of 5S and 18S-28S RNAosomal RNA genes) are generally dispersed in the genome and do not form large tandem arrays with varying copy number.
During the last decade, large efforts have been concentrated on genome sequencing of ascomycetes, and only a few basidiomycetes genomes were made available.
This disagreement probably arose because the previous study emphasised entire coding sequences, similarly to Figure 2. In comparison, our study concentrated on the sequence context of different substitutions.
Initial work concentrated on finding sequence-derived factors that are useful to determine crystallization propensity.
The conventional prediction methods usually concentrated on protein sequence homology through finding homologies of a protein based on their similarity.
The present study concentrated on glacigenic sediment sequences exposed along coastal erosional cliffs.
Several authors, including Ahmad and Mursaleen [2], Lorentz [1], King [3], Mohapatra [4, 5], Nanda [6], and other authors [7 10] have concentrated on almost convergent sequences.
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