Our specific gating strategy for Gr-1+ cells concentrated on cells that expressed high levels of Gr-1 and were also CD11b+ and CD11c-, which are suggestive of neutrophils [46] [49] (data not shown).
However, ChIP studies in general are primarily concentrated on cell-based studies, although its tissue-based application provides better understanding in respect of physiological and pathophysiological responses to a complex system.
Consequently, further investigations of lipid metabolism during apoptosis concentrated on cells treated with Fas mAb for up to 7 h when no secondary necrosis could be observed.
It has to be noted that there was no distinction between germline progenitors and oocytes using this genetic approach, and it appears that most experiments concentrated on cells of the size of meiotic oocytes.
Much of the work of the molecular era has concentrated on readily tractable cells, notably immortalized mammalian tissue culture cells, or powerful genetic systems such as yeast.
Optimization of bioprocesses with mammalian cells mainly concentrates on cell engineering, cell screening and medium optimization to achieve enhanced cell growth and productivity.
Some GO terms were enriched for genes from both climacteric and non-climacteric fruit groups, mainly concentrating on cell growth and morphogenesis, metabolic process as well as stress response.
Cytoskeleton models mostly concentrated on evaluating cell elasticity against cell deformation or material properties of cytoskeletal constituents [1], [8], [11].
Most work has concentrated on the cell division kinase (CDK) inhibitor, p21WAF1, which acts to arrest the cell cycle at the G1 to S phase and G2 to M phase transitions [ 18].
For the mammalian cell experiments, we concentrated on HeLa cells to facilitate morphological examination.
Most investigations to date have concentrated on the cell as both a target for and mediator of, ultraviolet radiation-induced photoageing.
