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Research Council, Sir Edward Mellanby, who discovered that dogs fed a concentrated diet of bread made of heavily agenized flour developed "canine hysteria".
When given increasing doses of a relatively concentrated diet (orange line), lifespan would increase as malnutrition lessens to a peak at an intermediate level of food availability.
The piglets were offered ad libitum access to a concentrated diet specialized for small piglets from the age of 2 weeks.
The goats were offered hay ad libitum and 0.4 kg and 1.2 kg per day of a standard concentrated diet in experiment 1 and 2 respectively.
The lowest income group also shows a greater tendency to substitute sugar sweetened drinks with fruit juice and concentrated diet soft drinks.
In production practice, impairment of intestinal epithelial barrier function is frequently found in high-producing ruminants which are usually fed a highly concentrated diet for relatively long time.
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There appear to be no metabolic advantage to increasing the supply of starch to the rumen or the abomasum of mid-lactation dairy cows maintained on highly concentrated diets and exhibiting a positive energy balance.
This tolerance developed even though rats exposed to the most concentrated diets ingested daily amounts of P. vulgaris extract 2 to 3 times higher than those ingested during the first days of treatment.
For non-concentrated sugar sweetened drinks, relatively large substitution effects (cross price value >0.10) occur for non-concentrated diet soft drinks, concentrated sugar sweetened drinks, milk, fruit juice, and tea and coffee (table 3).
Therefore, if one plans to evaluate massive VC, experimental animals must be fed higher concentrated adenine-diet for a longer period of time or must be observed after several months in the 5/6Nx model [ 25].
In the colostral period the same physiological pathways seem to bepresent, reaching a higher concentrated fatty acid diet for calves.
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