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While the classical "structure-based design" paradigm is still mostly conceived to be applicable in later lead optimization phases, the greatest impact will in fact be generated in the early project phases, hit finding, and validation.
Because NA is determined by considering both the thickness and elastic modulus of a buffer layer, the design rule is conceived to be applicable regardless of the material and thickness that are used for the buffer layer.
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Even though by extension it is often referred to as "ligand efficiency", the concept was originally conceived to be strictly applicable to comparing the binding efficiencies of ligands for a single target.
Keller said that he was "not a lawyer," but that it would be "hard to conceive of a prosecution of Julian Assange that wouldn't stretch the law to be applicable to us.
Those charges turned out not to be applicable in Alabama.
We wanted everything to consistently be applicable.
The strategy conceived and the protocol set-up should be applicable to other microalgal species such as Nannochloropsis and Chlorella, thus serving as a useful tool in Chlamydomonas oil research and algal biotechnology.
It may also be applicable to Galileo.
Such information, scientists believe, may be applicable to human diseases.
"They figure that might be applicable to computers," Mr. Buderi said.
Build up prototypes that will be applicable to the organization.
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