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In addition, some scientists argue that the search for chemokine-based therapeutics is hampered by the redundancy in the chemokine system (Horuk, 2009), while others advocate for a better conceived target selection and the improvement of drug dosage regimens (Schall & Proudfoot, 2011).
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Despite some half-baked devolution on the Celtic fringe, Labour has done its best to stifle what little was left of local-government autonomy in England by means of thousands of centrally conceived targets and initiatives.
The shortcomings of the current standards of care highlighted above underscore the pressing need for rationally conceived therapies targeted to the specific molecular pathways deregulated in primary brain tumors.
Originally conceived in Minneapolis' Target City Lights in 2012 as an 80m × 24m × 14m media facade artwork, vitreous appeared in 2015 as a large-scale projection, before its film incarnation appeared online, bearing a soundtrack by Nikolai von Sallwitz, only four days ago.
The maximum floor acceleration and total structural volume are conceived as soft targets that are incorporated as objective functions of the multiobjective programming problem.
A new scheme of internal target experiments is conceived where a quite thick target is installed and high repetition of beam injection is used from the injector cyclotron.
A backlash which is wrongly conceived and wrongly targeted … but not entirely unfounded.
Knowledge of tumor-specific metabolic pathway flux, obtainable via the emerging tool of stable isotope-based dynamic metabolic profiling (SIDMAP), identifies metabolic enzyme drug targets which might help to overcome difficulties related to resistance to currently evolving targeted therapies against more narrowly conceived gene or protein targets.
Conceived to target the Russian-speaking diaspora it is certainly an anomaly among Russian and Russian-speaking media channels.
He next surfaced in Thailand, where he is thought to have conceived a strategy to target vulnerable spots frequented by westerners in Bangkok, such as hotels and bars, rather than better protected embassies and aircraft.
Network interaction analysis of the target genes conceived four gene clusters - CDK4, TFAP2A, CDKN1A-p21 and ING1 linked by p53 and PCNA.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com