(For this reason, Harley recommends that his clients register not only their own names but every conceivable variant — Nu Balance, Neu Balan, New Barance).
Using this information, Dr. Lucas is working with the Armed Forces Institute of Pathology in Washington to publish an atlas of "every conceivable variant" of the way that H.I.V. can damage the body.
Rather than patenting every conceivable variant, the company claims jurisdiction over isolated DNA sequences, 15 base pairs long, that match short parts of the genes.
First, it is conceivable the variant weakens the affinity for SOX10 and/or creates a novel protein binding site that competes with SOX10.
It is conceivable that these variants have different target genes; thus certain types of miRNAs could inhibit multiple target genes.
It is conceivable that hyperactive variants are implicated in lymphomagenesis by increasing the frequency of off-target DNA damage.
It is conceivable that different variants of similar types of cancer may differ with regard to their metabolic behavior.
Based on our findings, it is conceivable that TGFBR2 variants may have prognostic and predictive value also for the outcome of TGF-ß signal inhibition.
It is conceivable that allelic variants in IFN-γ genes may influence the levels of released protein [ 11] which in turn could increase the susceptibility to leishmaniasis or predispose for progression to mucosal leishmaniasis.
Given that Cox-2 is highly developmentally regulated, it is conceivable that these allelic variants could upset the balance of gene expression in a developmental pathway as described above.
