It is conceivable that in order for bradyzoite formation to occur, a specific set of genes must be poised in the "off" position awaiting a signal that causes the induction of these genes, initiating the bradyzoite differentiation cascade.
A functional relationship of PTEN and SENP1 is conceivable because SENP1 induced SUMOylation is known to occur and to have biological impact in the PTEN/PI3K/AKT signaling pathway [ 33, 34].
Retirements are likely to occur later, and it is at least conceivable that some countries will even compete for immigrants.
It is also conceivable that B cell proliferation and plasma cell formation may continue to occur despite rituximab treatment.
This does not mean historical change ceases to occur, but that its unitary development is no longer conceivable, so only local histories are possible.
For example, in many neurodegenerative diseases, cells accumulate ubiquitin conjugates [ 38] and it is conceivable that under these conditions free ubiquitin is depleted enough for atypical NEDDylation to occur.
However, it is conceivable that transient interference with other morphogenic pathways may similarly prevent regeneration while allowing for wound healing to occur.
It is conceivable that the high rate of mutation accumulation in small intestine is due to replication errors, which are less likely to occur in the brain, a mainly postmitotic organ.
Intramuscular production of sVEGFR1 was assumed in this model to occur entirely through abluminal endothelial secretion into the interstitium; luminal endothelial secretion into the circulation is a conceivable direct blood source of sVEGFR1 but has yet to be quantitatively documented.
However, rather than loss of a single function, it is also conceivable and perhaps even more likely that a generalized weakening in microglial capabilities below a certain minimal essential level may have to occur in order for NFD to develop.
