Sentence examples for concealed trials from inspiring English sources

Moreover, Schulz et al. [ 47] found that odds reductions were exaggerated by up to 30% for trials that did not have clear concealment, and by 41% for inadequately concealed trials.

When the analysis was restricted to the 32 adequately concealed trials involving 3408 patients, tranexamic acid reduced the risk of receiving a blood transfusion by 32% (0.68, 0.62 to 0.74; P<0.001).

For example, Moher and his colleagues found a 34% greater estimate of treatment effect for low quality versus high quality trials and a 37% greater estimate of treatment effect for inadequately concealed versus adequately concealed trials associated with reviews addressing a variety of clinical conditions [ 5].

To reduce bias in the verification process, vignettes were carefully worded and followed specific rules aimed at concealing trial arm allocation from cause of death reviewers, such that any misclassification would be unrelated to trial arm.

In later trials, more concerted efforts have been taken to conceal trial arm and screening status from reviewers, through the submission of edited copies of the clinical record, with all personal identifiers and references to trial arm or screening status removed [ 1, 2, 4].

The strength of the CAP trial approach was in enabling researchers to carefully word vignettes to conceal trial arm and screening status, standardise terminology and include the same level of detail across trial arms, while providing sufficient information for accurate determination of UCD.

In recent years, police and prosecutors have been subjected to mounting criticism following revelations that key evidence gathered by undercover officers had been frequently concealed from trials of political campaigners.

PROphylaxis for ThromboEmbolism in Critical Care Trial (NCT00182143) is a randomized, stratified, concealed international trial comparing subcutaneous injection of unfractionated heparin (UFH) 5000 IU or the low molecular weight heparin (LMWH) dalteparin 5000 IU once daily plus once-daily placebo for the duration of the intensive care unit stay.

This pragmatic, multicenter, nationwide, randomized, concealed, controlled trial was designed to investigate the effects of the BALANCE Program in reducing cardiovascular events.

Materials & methods: Eighty five infertile women with PCOS participated in a randomized allocation concealed prospective trial and had induction of ovulation with clomiphene citrate.

But he also said there are few reasons why unclassified evidence should be concealed at trial.