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The algorithm for computing the score (or 'tariff', as referred to by some) is straightforward.
We have selected JTT evolutionary substitution model for amino acid replacements and Bayesian method for computing the score.
Computing the score for any one of these extensions can be done in constant time, given the earlier precomputation of match scores.
For example, the algorithm for computing the score for the health state 21223 is: 1 - (0.081 + 0.069 + 0 + 0.036 + 0.123 + 0.236 + 0.269) = 0.186 In order to eliminate the possible influence that social preferences may have on the EQ-5D index score, we developed an unweighted scoring rule based solely on answers provided by subjects to the Descriptive system.
For example, the algorithm for computing the score for the health state 21223 is: [(1 - ((1 + 0 + 1 + 1 + 2)/ 10)] · 1.59 - 0.59 = 0.205 Considering that the objective of the study was to compare the weighted and unweighted scores of the EQ-5D, the analysis described below could be performed on any sample of subjects answering the EQ-5D (results would be invariant).
However, computing the score of all possible states in atomistic detail is considered computationally intractable (Istrail, 2000), so our approach uses a philosophy of domain restriction (via schemas) to efficiently predict accurate, physically meaningful amyloid structures at the level of super-secondary structure.
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The results for ranking the markers based on the USA dataset and computing the scores using the Netherlands set are shown in Fig. 4D.
As β decreases, the neighborhood size increases, and more neighboring genes are considered for computing the scores of the candidates (see Table S9).
We do not use a threshold to distinguish between highly and lowly differentially expressed genes, because our method considers all differential expression levels for computing the scores.
In computing the scores in Equation 2, S ranges over all the nodes in the tree traversal except the root.
Finally, computing the scores of all blocks B i, j with their sizes bounded by r takes O(mr).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com