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For computing the baseline for stress classification, a SVM was used.
Williams et al [ 2] proposed a robust algorithm for computing the baseline correction of MALDI-MS spectra.
We note that, unlike the standard Cox regression setting, computing the baseline hazard is necessary to compute the conditional means.
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A three-dimensional, implicit, multi-species fuel cell solver is developed to compute the baseline solution.
We then computed the baseline (or the expected) peptide-similarity as the average random similarity denoted SE.
(An analogous algorithm is applied to compute the baseline tolerance of genes in accordance to the three other classification systems).
We computed the baseline cost for ECV to be $1,024, similar to that determined by Gifford et al [ 31].
Therefore, we clustered the genes according to functional criteria (as described in Materials and methods) and then computed the baseline tolerance of these groups of functionally related genes.
In this study, we computed the baseline partial pathlength with detected light within the brain as opposed to the traditional calculation [ 21, 38] in which only the region of activation is considered.
Note that the inferior limit of 20 SNVs to compute the baseline tolerance (described in the 'Detecting differences in baseline tolerance across genes' section) applies not to a single gene but rather to the SNVs pooled from genes within the same functional group(s).
Pooling the scored nsSNVs of the three most specific GOMF terms (phosphatidylinositol-4,5-bisphosphate 3-kinase activity, 1-phosphatidylinositol-3-kinase activity, inositol or phosphatidylinositol kinase activity) satisfies the condition of using at least 20 nsSNVs to compute the baseline tolerance of a gene.
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