MUSCLE was used because it gives a better accuracy and is computationally stronger than CLUSTAL alignment [ 41].
Typical analog integrated circuit optimization problems are computationally hard and require the handling of multiple, conflicting, and non-commensurate objectives having strong nonlinear interdependence.
Specifically, some of the variant positions in this set exhibited (computationally-determined) strong correlations with other positions in the protein, suggesting that this particular feature also made a difference.
Airoldi et al. [ 16] computationally predicted the strong up-regulation of growth as a response to the absence of appropriate nutrients.
Thus, strong and computationally demanding methods, placed on the bottom of the cascade, have to deal with less features.
This allows the proposed WSNM to be computationally faster than a pathwise (strong) stochastic Newmark method, proposed recently (J. Sound Vib. 249 (2002) 83).
Strong interactions were computationally determined between acidic functional monomers like methacrylic acid (MAA) or itaconic acid (IA) with triazines, and between vinylimidazole with bentazone and bromoxynil.
This encryption should be stronger and less computationally taxing.
Therefore it is for strong inputs no longer computationally feasible to numerically solve the full master equation.
Therefore, to get a sufficiently small discretization error, one must choose very small time-steps, which means that the method becomes computationally expensive and also causes a stronger increase of round-off errors.
Such multiple binding registers have been computationally predicted to be fairly prevalent in strong binders [26], [34] and have also been experimentally observed [48], [49], [50].
