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However, to obtain all the minimal solutions to (Acircmathbf{x} = mathbf{b}) is in general a computationally difficult task because the number of minimal solutions could be exponentially large with respect to the input size.
However, aligning even a single pair of networks is a computationally difficult task.
Network comparison is also a computationally difficult task because typical PPI networks are relatively large, e.g. Saccharomyces cerevisiae already has about 18 440 binary PPIs in the DIP™ database.
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Graph clustering is a computationally challenging and difficult task, especially for big graph data.
The numerical integration algorithm for the dynamic equation is modified to eliminate the need of measuring input forces, and a substructuring strategy is necessarily incorporated to overcome the otherwise computationally difficult (if not impossible) task.
Computer-aided 3D IC layout design task is computationally difficult and no deterministic polynomial time algorithms are able to solve it.
Such tasks are computationally difficult, so a number of search heuristics have been proposed: for example, PathBLAST uses randomized dynamic programming to search for conserved pathways across networks, while NetworkBLAST-E implements a greedy heuristic to search for conserved protein complexes.
Because of the high level of sequence similarity shared with the parent genes, the genes from which they were mostly likely generated, it has been a difficult task to biochemically and computationally distinguish pseudogenes from genes.
It's a difficult task.
Ms. Minor's most difficult task?
"That is really not a difficult task".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com