Sentence examples for computational shortcomings from inspiring English sources

Use of this transformation eliminates computational shortcomings linked to proportions when using multivariate techniques such as 2b-PLS, due to the fact that a spurious correlation effect between variables is introduced by the unit-sum constraint when transforming absolute quantities into relative ones, making the covariance matrix of a compositional space singular [47], [48].

From the point of view of applications, however, circumscription has a major computational shortcoming, which is due to the nature of the second-order language in which circumscription is formulated.

In spite of these shortcomings, computational methods have offered a route towards blueprints for these hydrophobic proteins.

In response to these shortcomings, computational methods for the prediction of PPISs have been developed, starting with Jones and Thornton's pioneering analysis of surface patches [ 5, 6], and many predictors have since been published [ 7- 43], utilizing a wide variety of algorithmic approaches to the problem.

Despite the computational difficulties and potential shortcomings of specific steps in their construction, supermatrix methods allow for simultaneous data analysis.

The underestimations are largely due to shortcomings of computational procedures used to generate the ensembles based on NMR data.

This often represents a shortcoming of computational publications and limits the general utility of computational methods (especially when specifically curated data are used to establish them).

Specifically, existing methods in computational biology share this shortcoming, as well as additional computational limitations, prohibiting their effective applications to the large datasets including a large number of genes and many data points.

A lot of research has gone into developing computer programs that can identify these variants automatically, but computational approaches have some significant shortcomings, especially when identifying indels in certain types of genomes, such as genomes that are highly repetitive or contain a lot of cytosine (C) and guanine (G) bases.

Moreover, factorization of the desired covariance matrix is avoided to overcome the shortcomings and high computational complexity of conventional methods.

While our results thus avoid these criticisms, since Levine et al.'s criticisms were meant to illustrate the general shortcomings of computer modeling, our results also argue against excessive skepticism about computational approaches in epidemiology.