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The core computational phase is designed to embarrassingly parallelize the computations, iterating through SNP pairs and efficiently carrying out the tests for epistasis.
LPOD and LDEIM use classification approach to find these regions in the offline computational phase.
We show that finding high-multiplexing/high-coverage designs is subject to a computational phase transition, becoming dramatically more difficult when the probability of primer pair interaction exceeds a critical threshold.
We show that the problem of finding high-multiplexing/high-coverage designs is subject to a computational phase transition, becoming dramatically more difficult when the probability that two primers are mutually compatible drops below a critical threshold.
In addition, the definition of the mathematical model benefited from a preliminary bioinformatic process based on three-dimensional protein structure modeling, to confirm the actual spatio-temporal cascade of PRR interactions, and on a successive computational phase based on parameter sweep analysis and sensitivity analysis, to test the reliability of the chosen model parameterization.
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Sebastian, A. et al. Temporal correlation detection using computational phase-change memory.
To compute all possible trajectories corresponding to all possible boundary conditions, the technique is of computational order O(N \log N), where N is the total number of points in the computational phase-space domain; any particular set of boundary conditions is then extracted through rapid post-processing.
Using an explicit hydrodynamics proxy application from the U.S. Department of Energy, LULESH, we show how code optimizations impact different computational phases of the simulation.
A MapReduce job is modelled as a sequence of two computational phases, the map and the reduce phase.
Since computational phasing of diploid nuclear loci can be more accurate than cloning in separating alleles from heterozygous individuals [47], gametic phases for atpsβ were inferred using Phase [48], [49] as implemented in DnaSP [50].
Few studies used laboratory procedures in conjunction with computational phasing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com