In this review, we summarize some of the recent work in emerging computational imaging, sensing and diagnostics techniques, along with some of the complementary non-computational modalities that can potentially transform the delivery of health care globally.
Since the eventual goal of biomedical research is the identification and development of therapeutic modalities, computational representation must have sufficient detail to facilitate this 'engineering' process.
A methodology to integrate medical imaging modalities with rigorous computational fluid dynamics entitled image-based computational fluid dynamics (iCFD) will be introduced.
Furthermore, the computational cost of individual modality decoders is increasing considerably, with many suggesting parallel processing implementations [46], [47].
Then the worst case computational complexity of the modality splitting stage is.
Notably, while the olfactory system solves essentially similar conceptual problems to other sensory systems, such as contrast enhancement, activity normalization, and extending dynamic range, its peculiarities often require qualitatively different computational algorithms than are deployed in other sensory modalities.
The development of additional strains permitting spectrally-distinct high-resolution live cell in vivo imaging, coupled to advances in optical imaging modalities and the development of improved computational methods to mine imaging data should pave the way for a multidimensional understanding of biological processes.
For further detail see Halpern and Vardi (1989), Fagin et al. (1995), as well as the more recent van Benthem and Pacuit (2006) which surveys a number of decidablity and undecidablity results concerning temporal-epistemic logics and illustrates again the crucial effect on the computational complexity which the combination of temporal and other modalities can bring about.
Using a computational model of ChR2(H134R mutant), we show that both stimulation modalities produce similar-in-morphology APs in human cardiomyocytes, and that electrical and optical excitability vary with cell type in a similar fashion.
As a response to these challenges, software environments and tools must be extensible in data modalities as well as scalable in storage and computational resources.
