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Several earlier modelling papers investigated such systems (some summarized in Jilkine and Edelstein-Keshet 2011 PLoS Comput Biol), thus the computational finding is not really surprising from the theoretical point of view, but together with the experimental validation the manuscript has merit.
Consistent with our computational finding, adult Stat1-null mice exhibit reduced numbers of CFU-E and elevated erythroblast apoptosis [ 26].
In 2011, Li et al. reported that HNF-4alpha is a key regulator positively controlling the expression of miR-122 in liver [ 37], proving our computational finding.
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A sample of computational findings was initially presented in Chawynski et al. (2003).
We carry out large scale Monte-Carlo simulation and our computational findings are extremely encouraging.
The computational findings were then used to guide structure-based optimization of the interfacial salt-bridge network.
For all considered polymers our computational findings clearly demonstrate that increasing the polymer concentration leads to the overcharging of the DNA molecule.
The computational findings add to our understanding of the catalytic mechanism of xanthine oxidase, and also assist the screening of mechanism-based inhibitors for this important drug target.
These psychophysical and computational findings suggest that stereoscopic transparency depends on both inter-neural interactions of disparity-tuned cells and higher-level processes governing figure ground segregation.
Our computational findings suggest a new concept for optical tuning of curved [8]circulenes through conformational isomerization and aromaticity control, thus through structural variations without changing the molecular composition.
Our molecular modeling results demonstrate that amyloid fibrils are extremely stiff with a Young's modulus in the range of 18 30 GPa, in good agreement with previous experimental and computational findings.
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CEO of Professional Science Editing for Scientists @ prosciediting.com