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The trivector approach allows us to release the extensor mechanism without performing major incisions on it and without compromising its function, which has been reported by Fischer et al. to occur with a standard medial trivector approach [9].
It is impossible to completely sterilize tissue without compromising its function and integrity.
Both of these interventions increased the available amount of SIRT1, likely enhancing the protein's ability to repair the DNA damage that leads to cancer without compromising its function as a gene regulator.
Exon skipping results in a partial truncation of the HECT-domain in the UBE3B protein, likely compromising its function.
This procedure was reported for the first time in 2006 [ 15] with the aim of restoring the neovagina without compromising its function.
In addition, more than 50% of colon tumors with defects in mismatch repair harbor mutations in Bax, thereby compromising its function in apoptosis [ 11].
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These data demonstrated that MWCNT 1 affected the BMP signaling pathway by binding to BMPR2 and compromising its signaling function.
This results in scar tissue formation and opacity of the cornea thus compromising its optical function [ 2].
The not4L35A mutation disrupts interactions between Not4 and its two known E2 ubiquitin-conjugating enzymes, Ubc4 and Ubc5, thus compromising its ubiquitin ligase function [63].
Accumulation of nitrogenous compounds (Rodrigues et al. 2012), chemical substances present in water (Roberts 2012) and ectoparasites (Valladão et al. 2013) can cause severe alterations in gill structure, compromising the function of its filaments.
The aberrant expression of class II antigens could also compromise production of immunoregulatory cytokines, compromising immune function and perhaps favor viral persistence through escape from immune recognition.
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disrupting its function
compromising its capability
compromising its performance
compromising its position
decreasing its function
impair its function
compromising its durability
compromising its integrity
compromising its role
compromising its trafficking
compromising its mission
compromising its estimate
compromising its ability
compromising its selectivity
compromising its virility
compromising its adsorption
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