Sentence examples for compromising function from inspiring English sources

Redundancy within the dystrophin protein allows some domains to be removed without seriously compromising function.

This damage extends to the mitochondrial respiratory components themselves, compromising function further.

So, a timing-robust organism may freely vary reaction rates without compromising function, allowing evolution to fine-tune and optimize functions smoothly.

Because the active sites of TIM barrel enzymes are invariably comprised of the loops protruding from the C-termini of the β-strands, engineering βα-hairpin clamps at the N-termini of the β-strands offer a unique opportunity to enhance the stability of TIM barrel proteins without compromising function.

This suggests that the mutation causes disease by compromising function, rather than impairing protein localization to the cell surface.

Adding excess membrane to other subcellular organelles would effectively dilute the protein components, thus also compromising function.

The dominant nature of the disease is therefore explained by the fact that the mutant protein present in these filaments does not function properly, thus compromising the function of the entire filament.

Therefore, we hypothesize that AngII may play an important role in compromising microvascular function and thus provide another potential link between obesity and obesity-related microvascular dysfunction.

Reactive oxygen species are increasingly recognized to play an important role in compromising endothelial function, including modulation of vasomotor tone [ 12, 13].

The aberrant expression of class II antigens could also compromise production of immunoregulatory cytokines, compromising immune function and perhaps favor viral persistence through escape from immune recognition.

Taken together, these results demonstrate that KDAC inhibition affects azole resistance in a manner that phenocopies Hsp90 inhibition, supporting the model that compromising KDAC function leads to impaired Hsp90 function, thereby blocking stress responses critical for azole resistance.