Sentence examples for compromising dose from inspiring English sources

7 Catheter-related sepsis indirectly affects outcomes of chemotherapy by compromising dose intensity, 23 is associated with significant morbidity and increased health care costs, 24– 27 and is fatal in approximately 15% of patients.

In this Australian phase II study in untreated patients with metastatic colorectal cancer, we also sought to simplify the treatment delivery schedule of the active FOLFOX4 regimen without compromising dose intensity.

We demonstrate that the addition of low dose paclitaxel allows delivery of weekly dose dense carboplatin AUC 3 by maintaining platelet counts without compromising dose dense carboplatin mediated tumour response.

In the present case series we have demonstrated that the addition of low dose paclitaxel allows delivery of weekly dose dense carboplatin AUC 3 by maintaining platelet counts without compromising dose dense carboplatin mediated tumour response.

Thus, to guarantee outcomes similar to those seen in the ATN and RENAL studies and to have confidence that an effective dose of CRRT has been delivered, clinicians should prescribe 20 to 30 mL/kg per hour on the basis of body weight at time of commencement of CRRT and ensure that excessive periods off of treatment are not compromising dose delivered.

In addition, partial loss of Int6 causes embryos to be highly sensitive to a mildly compromising dose of Mek inhibition, revealing an in vivo interaction between Int6 protein expression and developmental Mek-Erk signaling (Figure 4).

However, as Leonard has pointed out (Leonard et al, 2003), compromising the dose of chemotherapy in adjuvant treatment of breast cancer may also compromise efficacy.

In conclusion, aligning the PTV center with the machine's rotational axis by shifting the patient during tomotherapy reduces the delivery time without compromising the dose quality of intensity-modulated radiation therapy.

This study determined the efficacy and safety of a modified FOLFOX regimen that improved patient convenience without compromising oxaliplatin dose intensity.

This could be achieved without compromising the doses to the target volumes.

The dosimetric analysis revealed that a 1-mm uniform margin was sufficient to ensure the CTV dose coverage, without compromising the OAR dose tolerances.