We emphasize that parotid dose reduction does not compromise target coverage as there was no difference in PTV coverage between the two groups.
For delivery purposes the nNP-ricin vector must not heavily compromise target cell protein synthesis, as such, no less than 75% protein synthesis must still occur in the MC57 target cells.
However, these highly engineered liposomes generate new problems, such as accelerated clearance from circulation, compromised targeting owing to non-specific serum protein binding, and hindered tumor penetration.
Finally, we need to ask: If companies that use software exploits to compromise targets in the public interest come to learn that other, less savory individuals are using the same exploits for ignoble purposes, do they have an obligation to disclose the problem?
Kirk directs the Enterprise into the nearby Mutara Nebula; static discharges inside the nebula render shields useless and compromise targeting systems, making the Enterprise and the Reliant evenly matched.
Disruption of bundle formation, either through treatment with Latrunculin A (LatA) or following expression of a dominant-negative form of mDia1, led to compromised targeting of the secretory process.
The reactivation of TEs is often coupled with disruption of chromatin-based epigenetic controlling mechanisms in the hybrid genome, like loss or re-patterning of cytosine methylation and compromised targeting by small interference (si) RNAs [ 9- 11].
But the Q5 compromises on target demographic, too.
In patients where bony structures had to be included, e.g. cervical spine, symmetrical irradiation was ensured in order to avoid asymmetric bone growth whenever possible without compromises in target coverage and without exceeding the tolerance dose of normal tissue structures.
Terms from his novels — "honey trap," for instance, to denote using sex to compromise a target — have been adopted by the pros.
