Intestinal epithelial barrier function may be compromised in response to PAR2 activation [ 55].
In addition to M. marinum, these animals were compromised in response to a second intracellular pathogen, Listeria monocytogenes.
Consequently, there is some evidence that single and double strand break repair functions may be compromised in response to AOM treatment.
Whilst classically vascular stiffness is directly related to ventricular stiffness and diastolic function, our study indicates that LV systolic function can be compromised in response to ventricular- vascular stiffening in patients with moderate CKD.
38 This indicates that brief explosiveness is compromised in response to match-play tennis in HOT and COOL conditions, but that reorganisation strategies during movements with longer active states may compensate for this impairment.
The effect of this is either legislative paralysis or suboptimal, Rube Goldberg-esque, patched-together-compromises, often made in response to crises with no due diligence.
We and others have demonstrated that phosphorylation of S345 is critical for an intact checkpoint response, as mutations of this site that prevent phosphorylation compromise cellular survival in response to DNA damage [12], [16].
Therefore, LCKS59A did not compromise TCR signalling in response to agonist and weak agonist ligands and it even led to slightly enhanced T-cell responses.
Disease or insults trigger acute events, secondary and chronic sequelae, including inflammation, wound healing, and adaptive changes that the compromised body undergoes in response to the unhealthy state.
In the current study, we present data supporting the hypothesis that the complexation of CisPt with the cytoplasmic ligand carnosine was compromised, most likely, in response to mechanical stress application.
