Sentence examples for compromised specificity from inspiring English sources

We could improve VarScan2 sensitivity after tuning the minimum allele fraction cut-off from the default 0.20 to a lower value, but at the cost of significantly compromised specificity (data not shown).

The increased sensitivity and additional amplification step of nested NAT assays is thought especially to be coupled with compromised specificity resulting from false positive results.

Tuberculin skin test (TST) has been the classical method used for LTBI diagnosis in spite of its compromised specificity due to cross-reaction with Mycobacterium bovis bacillus Calmette Guérin (BCG) vaccine strain and non-tuberculous mycobacteria.

Increasing clinical sensitivity should not compromise specificity.

We conclude that partial substitution of adenosine with DAP does not significantly compromise specificity and was, therefore, investigated further.

Nevertheless, the low cut-off values in A-TAC did not compromise specificity overall, except in the case of LDs (sensitivity 78% and specificity 64%).

It is therefore preferable to use scales and cut-offs with a very high sensitivity, even though this usually compromises specificity.

Abandoning the requirement for an extra reference MRI after 30 days does not compromise specificity, 28 and therefore the Panel, in its current revision of the McDonald Criteria, allows a new T2 lesion to establish DIT irrespective of the timing of the baseline MRI.

This can improve assay specificity because primer design parameters for the first stage of the SNP genotyping process are not compromised in specificity for optimal parameters that may be different for the next stage of amplification.

Unfortunately in the critical care setting, where organs other than the heart are usually compromised, the specificity of these markers, including tumor necrosis factor (TNF -α, CD-40L, inTNF -αkins (IL-18, IL-6, IL-33, and IL-1a), CRP, fibrinogen, pentraxin 3, and matrix metalloproteinases, are markedly comprominterleukins

However, this might have compromised the specificity, given the high homology between the cry1A.105 element and other cry elements.