Sentence examples for compromised protective from inspiring English sources

Consistently, compared to CDC1551, HN878-infected rabbit lungs show progressively increasing inflammation, suboptimal activation of macrophages and compromised protective Th1 responses from 4 to 12 weeks post-infection, at which time the animals have established chronic cavitary disease [ 12, 13].

It has been known for some time that high-fat diets can generally compromise protective immune responses [16], [17].

Dietary selenium is known to protect skin against UV-induced damage and cancer and its topical application improves skin surface parameters in humans, while selenium deficiency compromises protective antioxidant enzymes in skin.

However, repeated cycles of B-cell depletion may seriously compromise protective humoral immunity [ 42].

Interestingly, one study reported that neonatal treatment of female rats with testosterone, to mimic the transient elevations occurring naturally in males, compromised the protective effect of estradiol in the 6-OHDA model of PD (Moroz et al., 2003).

Experiments conducted in immunocompetent mice revealed that the hyper-attenuated profile observed with MTBVAC erp− strain did not compromise its protective efficacy profile in comparison with BCG.

Since conditions that destabilize the native state of a protein render the macromolecular system more prone to aggregation, we decided to investigate whether the CuII-induced alterations in Ub structure and stability may promote Ub aggregation and, thus, potentially compromise the protective function of the UPS in neurons.

Of morbidities that potentially compromise the protective mechanisms of the heart, DM appears primarily important to study today.

Because smoking compromises the protective barriers in airways, it has been linked to increased risk for many lung infections (36 ).

Many in vitro and in vivo studies have shown that acute extracellular acidification will compromise fundamental protective cellular responses and enhance tumor response to hyperthermia and chemotherapy.

Nitrosative and oxidative stress can also alter the solubility of parkin via posttranslational modification of cysteine residues, which may concomitantly compromise its protective function [ 106– 108].