Sentence examples for compromised functioning from inspiring English sources

The mutation can cause loss of function of the protein by dominant negative effects, or reduced or compromised functioning.

Altogether, the present results indicate compromised functioning of MDD in resistance to affective interference and inhibiting spontaneous emotional responses and supported the assumption that MDD emotion dysregulation is spanning negative as well as positive affect.

Compromised functioning of these two transmitter systems contributes to chronic pain states.

These data highlight the need for a range of functional studies to be performed in order to identify variants with partially compromised function.

Routine culture of primary hepatocytes is difficult and cumbersome due to their ability to develop compromised function.

However, it is not known which of these proteins shows compromised function that may play a key pathogenic role.

Indeed, perhaps compromised function of the proteasome and autophagy arising from such intermediates may be the principal toxic insult to the cell (see below).

The cut-off chosen represents the lowest octile of the score distribution in working populations and indicates a severely compromised function.

In the case of MSC12 and MSC16, both may have compromised function of the small subunit in the mitochondrial ribosome due to lower abundance of the RPS7 protein.

Children like adults are also prone for various oral disorders, all of which can likely compromise functioning, well-being and QoL [ 17].

Hypermethylation of the rDNA may compromise function and affect protein synthesis [ 29].