Sentence examples for compromised function from inspiring English sources

These data highlight the need for a range of functional studies to be performed in order to identify variants with partially compromised function.

Routine culture of primary hepatocytes is difficult and cumbersome due to their ability to develop compromised function.

While higher percentages of CD4+ effector/memory T-cells were found in old mice, the majority of T-cells were hyporesponsive as indicated by prolonged graft survival and compromised function in MLR and ELISPOT analysis.

However, it is not known which of these proteins shows compromised function that may play a key pathogenic role.

Indeed, perhaps compromised function of the proteasome and autophagy arising from such intermediates may be the principal toxic insult to the cell (see below).

The cut-off chosen represents the lowest octile of the score distribution in working populations and indicates a severely compromised function.

The mutation can cause loss of function of the protein by dominant negative effects, or reduced or compromised functioning.

Hypermethylation of the rDNA may compromise function and affect protein synthesis [ 29].

Other missense mutations might only partially compromise function and behave as risk alleles [ 29].

Secondary musculoskeletal impairments such as contracture, deformity, and osteoporosis can occur and further compromise function.

This difference in Hsp101 expression between the two CT treatments may be caused by strongly compromised cellular function at 45 °C and only partially compromised cellular function at 42 °C.