Sentence examples for compromised formation from inspiring English sources

Furthermore, in Noc washout experiments with HeLa cells expressing MGRN1, MGRN1ΔR or C316DMGRN1 to study the MT network, the interphase cells showed that catalytic inactivation of MGRN1 distinctly compromised formation of a polymerized mesh – the MGRN1ΔR- or C316DMGRN1-expressing celag lag behind the MGRN1 cells by ∼30 min.

The data so far did not rule out the possibilities of compromised formation of MVBs or impaired lysosomal acidification and/or proteolysis.

Second, PD-linked parkin mutations significantly compromise formation of this complex.

Preventing PTMs of the critical amino acids in the Hsp70 dimer interface could compromise formation of the client-loading complex.

We find that mutations within either interface weaken heterodimerization of isolated half hinges in vitro but do not greatly compromise formation of cohesin rings in vivo.

Since all clones expressing the TRPM8 variants K423N and R475C responded relatively poorly to agonist treatment, one interpretation could be that each residue change may compromise formation of fully functional TRPM8 channels.

These properties are both compatible with the 3.5-fold larger permeability observed for the CYP86A33-RNAi periderm and are reasonable because a substandard chain-methylene population could compromise formation of a polyester-wax seal.

Unlike wild type cells, Als5pV326N cells showed minimal thioflavin T fluorescence, consistent with the idea that the mutation compromised amyloid formation.

In our experimental model, tissue perfusion is severely compromised following formation of the gastric tube; this effect is aggravated by systemic hypotension independent from cardiac output.

It resembles a closed-fracture animal model and there is no need to bolster the anabolic part of the fracture healing, as in an open fracture with compromised bone formation.

This is based on the observations that Dsc 2 is the first desmosomal component at the cell surface followed by Dsg 2 in MDCK cells (Burdett and Sullivan 2002) and that, in keratinocytes, N-terminally deleted Dsc 3, which compromised desmosome formation was still able to bind to β-catenin.