Sentence examples for compromised efficacy from inspiring English sources

In addition, the emergence of multidrug-resistant parasites has compromised efficacy of many of the frontline chemotherapy treatments.

However, our in vivo CTL response study indicated that LCP NP-based vaccine elicited a potent systemic immune response regardless of the existence and stage of tumors, ruling out the possibility that compromised efficacy resulted from unsuccessful induction of antigen-specific CTL response at a late stage.

However, as Leonard has pointed out (Leonard et al, 2003), compromising the dose of chemotherapy in adjuvant treatment of breast cancer may also compromise efficacy.

Prolonged port reversal not recommended due to recirculation which compromises efficacy Locks Fibrinolytic locks are not evaluated and are not yet recommended Dose of RRT Check previous KT/V in case of intermittent hemodialysis session and consider catheter replacement Education of the team.

The results of our 2-week study suggest that rapid initiation with a higher dose of quetiapine (up to 800 mg/d by Day 4) is well tolerated in patients with schizophrenia or schizoaffective disorders and does not compromise efficacy relative to the conventional initiation.

Artesunate (AS) was added to both SP and AQ because of uncertainties of how rising P. falciparum resistance to SP and AQ alone might compromise efficacy if the primary action of IPTi was due to parasite clearance.

Although race has not been shown to compromise efficacy (Fulton et al 1995), no BPH study has addressed the efficacy of doxazosin in black men.

However, side effects caused by toxicity to normal cells and tissues limit chemotherapy dose density and intensity, which may compromise efficacy.

In this context, triggering of a hypoxic response may compromise efficacy of γ-rays in inducing senescence, as we have here shown.

The major disadvantage of the drug is its high cost, a problem that has been mitigated to some extent by the demonstration that use of single, fixed doses does not compromise efficacy.

Study results have shown that the substitution of docetaxel for paclitaxel in a platinum-based doublet does not compromise efficacy, but that such substitution may confer benefits in terms of convenience to patients and toxicity.