The superficial compartment has compromised lymphatic drainage, while the lymphatic drainage of the deep compartment is contiguous with the cheek drainage.
Predisposing factors include prior trauma (e.g. abrasion, laceration, puncture wounds), tinea pedis, stasis dermatitis, compromised lymphatic drainage, and venous insufficiency.
Surgical incisions following joint arthrodesis can be considered high-risk as arthrodesis is an extensive and invasive surgery, involving more soft tissue trauma and subsequent inflammation than typical internal fixation [ 2], with significant postoperative swelling and compromised circulatory drainage of the distal limb being possible sequelae [ 2].
40 These results are early indications that liposuction is safe and will not additionally compromise lymphatic drainage, either in primary or secondary lymphedema.
Higher morbidity in cases suffering a longer APAC attack might be due to more extensive peripheral anterior synechiae (PAS) formation and pigment release which can compromise the drainage mechanism of the trabecular meshwork.
Previous researchers have demonstrated that lymph drainage is compromised following an attack of cellulitis.
Failure of LRP-1-related elimination of Aβ with age [ 49] or in conditions of hypoxia [ 43] may also increase the flow of soluble Aβ into perivascular drainage pathways already compromised by age changes in the artery walls themselves [ 23].
Pyometra is an uncommon condition occurring mainly in elderly postmenopausal females, and results when natural drainage of the uterine cavity is compromised.
Drainage of haematoma can be considered if the vision is compromised, if there is relative afferent pupillary defect or if proptosis is severe with the risk of corneal exposure.
Splenic abscesses may be associated with other conditions such as torsion of the vascular pedicle, which can compromise vascular supply or drainage of the spleen, resulting in congestion, hypoxia, and necrosis of the splenic parenchyma with potential abscess formation [ 2].
There is a consensus that drainage is required in cases of enlarging effusions despite antibiotics or compromised respiration [25, 27].
