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These patients may have severely compromised circulation and tissue hypoxia, yet because of peripheral vasoconstriction, their blood pressure may be in the normal range.
Importantly, it should also be added that, although most reports indicate compromised circulation in PES-positive people, some showed no difference (Tarkkanen et al., 2008 ).
Also, since there are no direct toxic effect on the kidneys per se like that seen in ethylene glycol, increased creatinine is likely rather a sign of more compromised circulation due to a more severe state of poisoning.
The focus on solely CDH patients, with their compromised circulation, may explain this high incidence.
One serious complication was found at the femoral site, with compromised circulation to the leg [ 70]; eventually, thrombectomy was required.
Unfortunately, the aforementioned studies by their observational design cannot answer the question whether renin is a risk factor or indicator reflecting neurohormonal activation due to compromised circulation.
Similar(51)
The chaotic nature of excitation and inefficient ventricular contraction in pathological ventricular arrhythmias frequently compromises circulation.
A growing number of clinical and experimental studies unambiguously show that pleural effusion (PLE) not only causes respiratory derangement but also may significantly compromise circulation [1 5].
These structural modifications are suspected to alter blood rheology, and can ultimately compromise circulation and lead to organ failure.
We think that OSAS also compromises circulation at the optic nerve head by causing hypoxia and vascular dysregulation in patients with NTG and, the glaucomatous damage was shown to be stable after nCPAP treatment [ 15].
However, this degree of hypercapnic acidosis did not markedly compromise circulation; heart rate and arterial pressure increased probably due to increased sympathetic activity, which also could have contributed to the increased pulmonary artery pressure.
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