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It has been shown that non-dominated solutions generated by MUST help decision makers choose the compromised assignment plan which is otherwise hard and time-consuming to obtain.
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Their functional assignment is compromised by our lack of solved structures of PH domains that bind to monophosphorylated PIs, or of other proteins in complex with phosphatidylinositol 4-phosphate (PtdIns(4 P), which is the most abundant monophosphorylated PI.
He argues that "strategic bombing proved in the end to be inadequate in its own terms for carrying out its principle assignments and was morally compromised by deliberate escalation against civilian populations".
A 24-h telephone unblinding service was provided by the Data Management Centre for instances where principal investigators (PIs) believed that treatment of an adverse event may be compromised by their not knowing the treatment assignment.
However, questionable semantic type assignments have been observed, which compromised the performance of the applications built upon them.
To evaluate the interobserver variability in the assignment of the American Society of Anesthesiologists Physical Status Classification (ASA-PSC) to compromised small animal patients amongst a group of veterinary anaesthetists.
However, the validity of conclusions drawn from both orthology assignment and phylogenetic tree reconstruction can be compromised by the high evolutionary rate particularly of microsporidian proteins (e.g., Brinkmann et al. 2005).
Critics, including former high-ranking law enforcement officers at LAX, have contended that changing the police assignment protocol that had been in place since 9/11 compromised the safety of screening areas.
It is clear that CpG/non-CpG assignment seriously compromises the accuracy of estimation of both the number of CpG and non-CpG changes, most notably in minimally-diverged sequences.
Compromise solution-based fitness assignment has been proposed by Cheng and Gen (1998) as a means to obtain a compromised solution instead of generating all Pareto optimal solutions.
Power may also be slightly compromised in our combined-species analysis by minor divergences among species in mutation profiles or preferred/unpreferred codon assignments.
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